ATTR-CM experimental treatments

Cliramitug

Cliramitug is an experimental therapy being developed for ATTR-CM. Administered via infusions directly into the bloodstream, the medication is designed to promote the clearance of TTR clumps.

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Coramitug

Coramitug is an investigational TTR aggregate-clearing therapy given via infusions into the bloodstream.

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Eplontersen

Eplontersen is an experimental injectable therapy in development for ATTR-CM that works by reducing production of the TTR protein, thereby preventing its clumping. It is given via under-the-skin injections.

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Nexiguran ziclumeran

Nexiguran ziclumeran is an investigational gene-editing therapy being developed for ATTR-CM. Given as a one-time infusion into the bloodstream, the therapy is meant to suppress TTR production and aggregate formation.

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Nucresiran

Nucresiran is an investigational TTR-lowering therapy in development for ATTR-CM. It is administered through under-the-skin injections.

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