Discussion
ATTR-CM experimental treatments
Cliramitug
Cliramitug is an experimental therapy being developed for ATTR-CM. Administered via infusions directly into the bloodstream, the medication is designed to promote the clearance of TTR clumps.
Coramitug
Coramitug is an investigational TTR aggregate-clearing therapy given via infusions into the bloodstream.
Eplontersen
Eplontersen is an experimental injectable therapy in development for ATTR-CM that works by reducing production of the TTR protein, thereby preventing its clumping. It is given via under-the-skin injections.
Nexiguran ziclumeran
Nexiguran ziclumeran is an investigational gene-editing therapy being developed for ATTR-CM. Given as a one-time infusion into the bloodstream, the therapy is meant to suppress TTR production and aggregate formation.
Nucresiran
Nucresiran is an investigational TTR-lowering therapy in development for ATTR-CM. It is administered through under-the-skin injections.